Regular inhaled beta agonist in asthma: effects on exacerbations and lung function.
نویسندگان
چکیده
منابع مشابه
Regular inhaled beta agonist in asthma: effects on exacerbations and lung function.
BACKGROUND A comparison of the effects of regular upsilon as needed inhaled beta agonist treatment on the control of asthma in the last 16 weeks of each of two 24 week treatment periods has been reported. This paper presents additional information on exacerbations of asthma and trends in lung function, airways hyperresponsiveness to methacholine, and bronchodilator responsiveness during the ent...
متن کاملEffects of inhaled beta agonist and corticosteroid treatment on nuclear transcription factors in bronchial mucosa in asthma.
BACKGROUND Inhaled corticosteroids and beta agonists are the most commonly used treatments in asthma and are often used together. Recent evidence suggests that many of the anti-inflammatory actions of corticosteroids are mediated by cross-talk between the activated glucocorticoid receptor (GR) and other transcription factors such as the pro-inflammatory nuclear factor kappa B (NFkappaB). Beta a...
متن کاملEscalating Inhaled Glucocorticoids to Prevent Asthma Exacerbations.
Inhaled glucocorticoids are pivotal to achieve asthma control and disease stability in both children and adults; despite their use, with or without other treatments, many patients with asthma have ongoing episodic disease exacerbations.1 Often, these are linked to provocative factors such as viral or bacterial infections, nonadherence to treatment, allergen exposure, and environmental air pollu...
متن کاملSevere exacerbations predict excess lung function decline in asthma.
Severe asthma exacerbations are periods of intense airway inflammation that have been hypothesised to contribute to structural changes in the airways. If so, accelerated lung function decline over time should be more prevalent in adult patients with asthma who have frequent exacerbations than those without, but to date this has not been demonstrated. A cohort study was performed in order to inv...
متن کاملEffects of early intervention with inhaled budesonide on lung function in newly diagnosed asthma.
STUDY OBJECTIVES Asthmatic patients lose lung function faster than normal subjects. The effectiveness of early intervention with inhaled corticosteroids on this decline in lung function is not established in recent-onset disease. DESIGN The Inhaled Steroid Treatment as Regular Therapy in Early Asthma study was a randomized, double-blind study in 7,165 patients (5 to 66 years old), with persis...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Thorax
سال: 1993
ISSN: 0040-6376
DOI: 10.1136/thx.48.2.134